About HeFH

What is HeFH?

HeFH is a genetic disorder that causes high levels of LDL cholesterol. When a person has HeFH, their body has too much LDL which can lead to early heart disease and other conditions. Children with HeFH have inherited a genetic mutation from one parent.

Symptoms of HeFH in children (pediatric hyperlipidemia) may include:

There is currently no cure for HeFH, but researchers are trying to develop new medications and potential treatments for familial hypercholesterolemia. Participation in the CLEAR Path 1 study may help scientists and doctors learn about the study medication and whether it can help lower LDL in children and teens with HeFH.