About HeFH

What is HeFH?

HeFH is a genetic disorder that causes high levels of LDL cholesterol. When a person has HeFH, their body has too much LDL which can lead to early heart disease and other conditions. Children with HeFH have inherited a genetic mutation from one parent.

Symptoms of HeFH in children (pediatric hyperlipidemia) may include:

• Fatty bumps on the skin
• Grayish-white rings around the corneas in the eyes

There is currently no cure for HeFH, but researchers are trying to develop new medications and potential treatments for familial hypercholesterolemia. Participation in the CLEAR Path 1 study may help scientists and doctors learn about the study medication and whether it can help lower LDL in children and teens with HeFH.